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  • Micro-Tag™ Platform
  • Technology
  • Applications
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any Drug target. Focused modalities.

Turn Challenging Targets Druggable

We confidently support targets that belong to almost any family. 

We boldly offer applications for four major therapeutic modalities. 

Scroll down for case studies.

Therapeutic Modalities

Small molecules

Small molecules

Small molecules

Typically these are chemicals with  molecular weight <1000 g/mol.

Peptides

Small molecules

Small molecules

Natural or chemically modified peptides of any length.

Degraders

Small molecules

Antibodies

These are chimeric chemicals with  molecular weight <1500 g/mol.

Antibodies

Small molecules

Antibodies

Fully assembled antibodies or its components (Fab, Fc).

Case Studies: Real-time step-gradient method

cMYC Case Study (Real-time step-gradient method) (pdf)

Download

KRAS Case Study (Real-time step-gradient method) (pdf)

Download

MAPK1 Case Study (Real-time step-gradient method) (pdf)

Download

Case Studies: Conventional T-agg Method

BCL6 Case Study (T-agg method) (pdf)

Download

DHFR Case Study (T-agg method) (pdf)

Download

KRAS Case Study (T-agg method) (pdf)

Download

MTH1 Case Study (T-agg method) (pdf)

Download

Target Examples: TRANSCRIPTION FACTORS

BCL9

BCL9

BCL9

  • Target family: BCL9-like
  • Length: 1499 aa
  • Engagement confidence: High

Check Uniprot

cMYC

BCL9

BCL9

  • Target family: HLH, Leuzine zipper
  • Length: 454 aa
  • Engagement confidence: Moderate

Check Uniprot

CHD4

BCL9

TEAD4

  • Target family: Zinc finger, disordered
  • Length: 1912 aa
  • Engagement confidence: High

Check Uniprot

TEAD4

TEAD4

TEAD4

  • Target family: Disordered
  • Length: 434 aa
  • Engagement confidence: Moderate

Check Uniprot

TBL1X

TEAD4

TBL1X

  • Target family: WD, Disordered
  • Length: 577 aa
  • Engagement confidence: High

Check Uniprot

ERG

TEAD4

TBL1X

  • Target family: Disordered
  • Length: 479 aa
  • Engagement confidence: High

Check Uniprot

TARGET Examples: Enzymes

KRAS

KRAS

KRAS

  • Target family: GTPase, RAS
  • Length: 189 aa
  • Engagement confidence: High

Check Uniprot

MTH1

KRAS

KRAS

  • Target family: Nudix hydrolase
  • Length: 156 aa
  • Engagement confidence: High

Check Uniprot

DHFR

KRAS

PDE10

  • Target family: Dihydrofolate reductase
  • Length: 187 aa
  • Engagement confidence: High

Check Uniprot

PDE10

PDE10

PDE10

  • Target family: PDEase, GAF
  • Length: 779 aa
  • Engagement confidence: High

Check Uniprot

PLK1

PDE10

UBE2N

  • Target family: POLO vox, Kinase
  • Length: 603 aa
  • Engagement confidence: High

Check Uniprot

UBE2N

PDE10

UBE2N

  • Target family: Ubiquitin conjugator
  • Length: 152 aa
  • Engagement confidence: High

Check Uniprot

TARGET Examples: Membrane proteins

EGFR

C5aR1

EGFR

  • Target family: Kinase, Disordered
  • Length: 1210 aa
  • Engagement confidence: High

Check Uniprot

B2AR

C5aR1

EGFR

  • Target family: PDZ binder, Disordered
  • Length: 413 aa
  • Engagement confidence: High

Check Uniprot

C5aR1

C5aR1

C5aR1

  • Target family: G protein receptor
  • Length: 350 aa
  • Engagement confidence: High

Check Uniprot

MCT4

GRP75

C5aR1

  • Target family: Monocarboxylate porter
  • Length: 465 aa
  • Engagement confidence: High

Check Uniprot

GRP75

GRP75

GRP75

  • Target family: HSP70
  • Length: 679 aa
  • Engagement confidence: Low

Check Uniprot

CD20

GRP75

GRP75

  • Target family: MS4A
  • Length: 297 aa
  • Engagement confidence: High

Check Uniprot

TARGET Examples: Other Targets

SKP2

KDM3A

SKP2

  • Target family: Leucine-rich repeat
  • Length: 424 aa
  • Engagement confidence: Moderate

Check Uniprot

P27

KDM3A

SKP2

  • Target family: Cyclin-dependent kinase
  • Length: 198 aa
  • Engagement confidence: Moderate

Check Uniprot

KDM3A

KDM3A

KDM3A

  • Target family: Zinc finger, LXXLL
  • Length: 1321
  • Engagement confidence: High

Check Uniprot
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San Diego, California, USA

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