Open Target Initiative (OTI)

Eligibility Criteria

The Open Target Initiative is a limited, application-based program. Participation is subject to the following eligibility requirements:

Eligible Participants

Academic research laboratories
Early-stage biotechnology companies (case-by-case)
Applicants must have in-house capability to perform cell-based assays

Eligible Drug Targets

Participation applies only to CellarisBio’s list of validated MICRO-TAG® targets
Targets must be selected from the current validated target catalog
Unvalidated or novel targets are not eligible under OTI

Target Limits

A maximum of three (3) targets per laboratory may be included
Target selection is subject to availability and confirmation by CellarisBio

Kit Scope

OTI participation is limited to a designated MICRO-TAG® Cellular Target Engagement Kit
Kits are provided for research use only (RUO)
Kits may not be resold, transferred, or used for commercial services

Financial Terms

Participants are required to pay a nominal OTI participation fee
Shipping and handling fees apply separately
The participation fee does not represent the commercial price of MICRO-TAG® reagents

OTI Terms

By participating in the Open Target Initiative, you agree to the following terms:

1. Purpose of the Program

The Open Target Initiative is designed to collaboratively expand cellular target engagement data using MICRO-TAG® technology across a broad range of validated targets.

OTI is not a commercial purchasing program and does not replace standard reagent ordering.

2. Data Generation & Sharing

Participants agree to:

Generate experimental data using MICRO-TAG® reagents for selected validated targets
Share raw and processed data with CellarisBio within three (3) months of kit purchase
Provide sufficient experimental context to allow interpretation of results

Data sharing may include:

Raw signal files
Processed curves and metrics (e.g., Tagg₅₀ where applicable)
Experimental conditions and controls

CellarisBio may use shared data for:

Internal validation and benchmarking
Aggregated analyses
Development of application notes or educational materials

3. Public Communication & Advocacy

Participants agree to contribute to at least one public-facing activity within six (6) months of kit purchase, which may include:

A webinar presentation
A blog post or written case study
A recorded interview or testimonial

The format and timing will be coordinated collaboratively and approved by the participant prior to publication.

4. Intellectual Property

A maximum of three (3) targets per laboratory may be included
Target selection is subject to availability and confirmation by CellarisBio

5. Confidentiality & Research Use

All reagents are provided for research use only
Data shared under OTI does not require disclosure of unpublished manuscripts or patent filings
Participants are responsible for ensuring compliance with their institutional policies

6. Program Limitations

OTI participation is time-limited and subject to availability
CellarisBio reserves the right to limit, pause, or conclude the program at any time
Participation in OTI does not guarantee future access to discounted reagents or services

7. Removal from Program

Failure to:

Share data within the specified timeframe, or
Participate in agreed public communication

may result in removal from the Open Target Initiative and ineligibility for future participation.

Final Notes

The Open Target Initiative is a collaborative research program intended to expand community knowledge of cellular target engagement. It is not a substitute for commercial use of MICRO-TAG® reagents.